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Home >> S&T Platforms >> National Genotyping Centre
The Spanish National Genotyping Centre (CeGen)
The Spanish National Genotyping Centre (Centro Nacional de Genotipado - CeGen ) is a service platform created by Genoma España to carry out large scale genotyping projects. The aim is to identify thousands of mutations per genome, in a high number of preferably human samples. This type of research was previously not possible in our country due to the lack of necessary infrastructure.
The CeGen will respond to the needs of the Spanish research groups through Spanish population genotyping services aimed at establishing the molecular bases of the most prevalent diseases of our environment and at understanding the genetic basis for the variation between individuals' responses to medicines.
It will also conduct its own research in these areas and will work together with other international platforms and consortiums of this field. It will ensure that its services are kept up to date by constantly incorporating state-of-the-art technologies.
In summary, the CeGen will result in clear social advantages, including à-la-carte therapy or customised medicine, estimating risk and predicting drug responses.
It will also offer genotyping services in relation to plants and other animals of economic relevance to our country whose genomes have been partially or fully sequenced.
Investment
€15.1 million in 5 years (2004-2008).
Structure
The Spanish National Genotyping Centre has a nodal structure:
Coordination Unit:
Director, Dr Jaime Bertranpetit, Pompeu Fabra University.
- Node 1. SNPlex (a medium to large scale genotyping technology capable of analysing 4 million genotypes per year), Taqman (a small to medium scale genotyping technology capable of analysing 625,000 genotypes per year).
Barcelona: Genomic Regulation Centre and Pompeu Fabra University (Director: Dr Xavier Estivill).
- Node 2. Illumina (a large scale genotyping technique capable of analysing 25 million genotypes per year) and Taqman.
Madrid: Spanish National Oncology Research Centre (CNIO) (Director: Dr Javier Benítez).
- Node 3. Sequenom (a medium to large scale genotyping technology capable of analysing 1.5 million genotypes per year) and SNPlex.
Santiago de Compostela: Santiago de Compostela University (Director: Dr Ángel Carracedo).
Current status
With its various techniques, the CeGen 's genotyping analysis capability is similar to that of any other country of our environment. Spain has gone from analysing a few genotypes per year to a capacity of 800,000 a week, which can double with only a few additional resources if the country so demands.
It has already had requests, and is providing services since June 2005.
