The organizational structure of Genoma España is shown below.

The Board of Trustees is the governing body entrusted with the management, administration and representation of the Foundation and which takes responsibility for managing its estate and fulfilling its purposes in an efficient and useful way.
President
| Name | Organization |
| Mr ROMÁN ARJONA GRACIA | Secretary General for Innovation MINISTRY OF ECONOMY AND COMPETITIVENESS |
Vice President
| Name | Organization |
| Ms PILAR FAJAS ABADÍA | Secretary General for Health MINISTRY OF HEALTH, SOCIAL POLICY AND EQUALITY |
Board Members
| Name | Organization |
| Not yet appointed | MINISTRY OF ECONOMY AND COMPETITIVENESS |
| Not yet appointed | MINISTRY OF ECONOMY AND COMPETITIVENESS |
| Mr JOSÉ J. NAVAS PALACIOS | General Manager of the Carlos III Health Institute MINISTRY OF ECONOMY AND COMPETITIVENESS |
| Ms LOURDES ARANA ULI | General Manager of FECYT MINISTRY OF ECONOMY AND COMPETITIVENESS |
| Not yet appointed | PRIME MINISTER'S ECONOMY BUREAU |
| Ms MERCEDES VNUESA SEBASTIÁN | Director-General of Public Health, Quality and Innovation MINISTRY OF HEALTH, SOCIAL POLICY AND EQUALITY |
| Not yet appointed | MINISTRY OF INDUSTRY, ENERGY AND TOURISM |
| Not yet appointed | MINISTRY OF AGRICULTURE, FOOD AND ENVIRONMENT |
| Mr FRANCISCO ANDRÉS TRIGUERO | Councilor for Innovation, Business and Employment GOVERNMENT OF NAVARRA |
| Mr FRANCISCO ANDRÉS TRIGUERO | Secretary General of Universities, Research and Technology ANDALUSIAN REGIONAL GOVERNMENT |
| Ms SAGRARIO PÉREZ CASTELLANOS | Director- General for the Basic Service Portfolio of the National Health Service and Pharmacy MINISTRY OF HEALTH, SOCIAL POLICY AND EQUALITY |
Rafael Camacho holds a bachelor’s degree in Pharmacy (University of Seville) and completed his postgraduate studies in Biochemistry and Molecular Biology, Biotechnology and Marine Biology. He has developed his career in the field of Innovation Management, both public and private.
He started his career in 1989 working for the Research Results Transfer Offfice at the University of Seville, where he specialized in technology transfer, industrial property and university-industry cooperation. Afterwards he held the position of Executive Director at the CESEAND (Centre of Services for European Affairs in Andalusia). In 2002 he joined the biotech company Newbiotechnic, SA (NBT) as Managing Director.
In 2006 he was in charge of setting up and managing the Technology Transfer Office for the Ministry of Health of the Andalusian Government, and in late 2008 he joined the management team of the Spanish Foundation for Science and Technology (FECYT)

Board of Trustees